Application of adjunct techniques in cytologic material in the diagnosis of rhabdomyosarcoma: Case report and review of the literature
A 4½‐yr‐old female presented with right‐sided pleural effusion and a retroperitoneal mass. Cytologic analysis of the pleural fluid yielded malignant small round blue cells, which were noncohesive, 3–4 times the size of lymphocytes. The malignant cells had hyperchromatic, pleomorphic nuclei with mode...
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Published in: | Diagnostic cytopathology Vol. 26; no. 6; pp. 384 - 386 |
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Main Authors: | , , , , , |
Format: | Journal Article |
Language: | English |
Published: |
New York
Wiley Subscription Services, Inc., A Wiley Company
01-06-2002
Wiley-Liss |
Subjects: | |
Online Access: | Get full text |
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Summary: | A 4½‐yr‐old female presented with right‐sided pleural effusion and a retroperitoneal mass. Cytologic analysis of the pleural fluid yielded malignant small round blue cells, which were noncohesive, 3–4 times the size of lymphocytes. The malignant cells had hyperchromatic, pleomorphic nuclei with moderate amounts of vacuolated cytoplasm. A few fiber‐shaped cells were also seen. Immunostains for desmin, muscle‐specific actin were positive; ultrastructural findings of thick and thin actin‐myosin filaments confirmed the diagnosis of embryonal rhabdomyosarcoma. This case illustrates the importance of performing appropriate immunohistochemical stains and ultrastructural studies on cytological material to arrive at a definitive diagnosis. Diagn. Cytopathol. 2002;26:384–386. © 2002 Wiley‐Liss, Inc. |
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Bibliography: | ArticleID:DC10069 ark:/67375/WNG-C14Q6T27-F istex:BF55428043971B602577779662B31BB28F08C678 ObjectType-Case Study-3 SourceType-Scholarly Journals-1 content type line 23 ObjectType-Review-1 ObjectType-Feature-5 ObjectType-Report-2 ObjectType-Article-4 |
ISSN: | 8755-1039 1097-0339 |
DOI: | 10.1002/dc.10069 |