Development and Implantation of a Biocompatible Auricular Prosthesis

• Published in: Biomedical engineering Vol. 49; no. 6; pp. 327 - 330
• Main Authors: Kasyanov, V. A., Pereira, F. D. A. S., Parfenov, V. A., Kudan, E. V., Bulanova, E. A., Khesuani, Yu. D., Mironov, V. A.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01-03-2016; Springer; Springer Nature B.V
• Subjects: 3D printing; Bending; Biocompatibility; Biomaterials; Biomedical engineering; Biomedical Engineering and Bioengineering; Biomimetic materials; Biomimetics; Engineering; Implantation; Implants, Artificial; Material properties; Mechanical properties; Polyurethane; Polyurethane resins; Prostheses; Prosthesis; Prosthetics; Surgical implants; Theory and Design; Three dimensional printing; Internal Geometry; Subcutaneous Implantation; Tissue Engineer Cartilage; Polyurethane; Porous Polyethylene
• ISSN: 0006-3398; 1573-8256
• DOI: 10.1007/s10527-016-9559-5

A patient-specific auricular prosthesis made of biocompatible non-biodegradable polyurethane with biomimetic mechanical properties was developed and printed using a 3D printer. A three-point bending study of the mechanical properties of printed samples of this material showed that the printed prosthesis is similar in its material properties to natural human aural cartilage. After subcutaneous implantation into mice the auricular prosthesis maintained its initial shape and size. Thus, 3D printing enables creation of a patient-specific biocompatible auricular prosthesis with biomimetic material properties and the ability to maintain the original shape and size after in vivo implantation.