PlantCHRs: A comprehensive database of plant chromatin remodeling factors

• Published in: Computational and structural biotechnology journal Vol. 21; pp. 4974 - 4987
• Main Authors: Yan, Hengyu, Liu, Fangyuan, Zhang, Guowei, Liu, Shuai, Ma, Weiwei, Yang, Ting, Li, Yubin, Yang, Jiaotong, Cui, Hailong
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01-01-2023; Research Network of Computational and Structural Biotechnology; Elsevier
• Subjects: Chromatin remodeling factors; Evolution; Plant; Snf2; Snf2; Database; Evolution; Plant; Chromatin remodeling factors
• ISSN: 2001-0370; 2001-0370
• DOI: 10.1016/j.csbj.2023.10.005

The Snf2 protein family is a group of ATP-dependent chromatin remodeling factors (CHRs) that play an essential role in gene expression regulation. In plants, Snf2 is involved in growth, development, as well as stress resistance. However, only a very limited number of experimentally validated Snf2 have been identified and reported, while the majority remaining undiscovered in most species . In this study, we predicted 3135 Snf2 proteins and 8398 chromatin remodeling complex (CRC) subunits in diverse plant species, and constructed the Plant Chromatin Remodeling Factors Database (PlantCHRs, http://www.functionalgenomics.cn/PlantCHRs/), which provide a comprehensive resource for researchers to access information about plant CHRs. We also developed an online tool capable of predicting CHRs and CRC subunits. Moreover, we investigated the distribution of Snf2 proteins in different species and observed a significant increase in the number of Snf2 proteins and the diversity of the Snf2 subfamily during the evolution, highlighting their evolutionary importance. By analyzing the expression patterns of the Snf2 genes in different tissues of maize and Arabidopsis, we found that the Snf2 proteins may show some conservation across different species in regulating plant growth and development. Over the all, we established a comprehensive database for plant CHRs, which will facilitate the researches on plant chromatin remodeling.