Frequent clinical and radiological manifestations of the Novel SARS-CoV-2: A review article

• Published in: Journal of family medicine and primary care Vol. 10; no. 1; pp. 122 - 126
• Main Authors: Alshoabi, Sultan, Alhazmi, Fahad, Abdulaal, Osamah, Gameraddin, Moawia, Algaberi, Ali, Hamid, Abdullgabbar, Alsultan, Kamal, Alamri, Abdulrahman
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer India Pvt. Ltd 01-01-2021; Medknow Publications and Media Pvt. Ltd; Wolters Kluwer - Medknow
• Subjects: Communicable diseases; Coronaviruses; CT imaging; Health aspects; Review; Severe acute respiratory syndrome; China; Clinical manifestations; COVID-19; ground-glass opacity; fever; CT features
• ISSN: 2249-4863; 2278-7135
• DOI: 10.4103/jfmpc.jfmpc_1985_20

Coronavirus disease 2019 (COVID-19) is a highly infectious disease caused by the novel "severe acute respiratory syndrome coronavirus-2" (SARS-CoV-2) and is rapidly spreading worldwide. This review is designed to highlight the most common clinical features and computed tomography (CT) signs of patients with COVID-19 and to elaborate the most significant signs indicative of COVID-19 diagnosis. This review involved five original articles with both clinical and radiological features of COVID-19 published during Jan and Mar 2020. In this review, the most frequent symptoms of COVID-19 were fever and cough. Myalgia, fatigue, sore throat, headache, diarrhea, and dyspnea were less common manifestations. Nausea and vomiting were rare. Ground-glass opacity (GGO) was the most common radiological finding on CT, and mixed GGO with consolidation was reported in some cases. In addition, elevated C-reactive protein and lymphopenia are the pertinent laboratory findings of COVID-19. CT is an effective and important imaging tool for both diagnosis and follow-up COVID-19 patients with varied features, duration, and course of the disease. Bilateral GGOs, especially in the periphery of the lungs with or without consolidation, are the hallmark of COVID-19.