Evaluation of the Antioxidant Potency of Seseli L. Species (Apiaceae)

• Published in: Turkish journal of pharmaceutical sciences Vol. 17; no. 2; pp. 197 - 202
• Main Authors: Önder, Alev, Çinar, Ahsen Sevde, Yilmaz Sarialtin, Sezen, Izgi, Mehmet Necat, Çoban, Tülay
• Format: Journal Article
• Language: English
• Published: Turkey Türk Eczacılar Birliği 01-04-2020; Galenos Publishing
• Subjects: Eczacılık; Original; Sağlık Hizmetleri; Tıp; Ankara; Türkiye; LPO; DPPH; Antioxidant; Apiaceae; Seseli; Antioksidan
• ISSN: 1304-530X; 2148-6247; 2148-6247
• DOI: 10.4274/tjps.galenos.2019.80488

In the present study, the antioxidant potency of ethyl acetate (AcOEt) and methanol (MeOH) extracts from the aerial parts of
L. species was investigated for the first time.
species L. such as
Woronow ex Schischk.,
Besser,
Boiss. & Heldr.,
subsp.
Pall. ex Sm.,
Parolly & Nordt,
(L.) W.Koch,
M.Bieb.,
(M.Bieb.) Koso-Pol.,
Freyn & Sint., and
L. growing in Turkey were collected and evaluated for their antioxidant capacity by using 1.1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging and lipid peroxidation (LPO) inhibition methods.
The highest activities as a scavenger of DPPH radicals were found in the AcOEt extracts of
(M.Bieb.) Koso-Pol (IC
=0.49 mg/mL), and
(IC
=0.75 mg/mL); α-tocopherol was used as a positive control. On the other hand, in the LPO assay, the highest activities were determined in AcOEt and MeOH extracts (at 5 mg/mL) of
and
(84-94%).
This report gives important information about the antioxidant capacity of
L. species. This research on antioxidant capacity proves that the use of some species used in Eastern Anatolia (in salads) is correct. With this screening study performed in
L. species growing in Turkey, in the future, it is planned to isolate antioxidant compounds from the most active strains of
L.