Neurofibroma of the breast in a boy with neurofibromatosis type 1

• Published in: Clinical imaging Vol. 28; no. 6; pp. 415 - 417
• Main Authors: Murat, Ayse, Kansiz, Fatma, Kabakus, Nimet, Kazez, Ahmet, Ozercan, Resat
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01-11-2004; Elsevier; Elsevier Limited
• Subjects: Biological and medical sciences; Biopsy, Needle; Breast; Breast Neoplasms - complications; Breast Neoplasms - diagnosis; Child; Children; Follow-Up Studies; Humans; Immunohistochemistry; Magnetic Resonance Imaging - methods; Male; Medical sciences; Neurofibroma - complications; Neurofibroma - diagnosis; Neurofibromatosis; Neurofibromatosis 1 - complications; Neurofibromatosis 1 - diagnosis; Neurology; Risk Assessment; Sensitivity and Specificity; Tumors of the nervous system. Phacomatoses; Breast; Neurofibromatosis; Children; Human; Skin disease; Nervous system diseases; Phacomatosis; Neurofibromatosis Recklinghausen; Genetic disease; Central nervous system disease; Benign neoplasm; Mammary gland; Child; Neurofibroma
• ISSN: 0899-7071; 1873-4499
• DOI: 10.1016/S0899-7071(04)00004-X

Neurofibromas occurring in the breast are very rare. A 10-year-old boy with neurofibromatosis type 1 (NF1) presented with a palpable mass on his left breast. US showed a well-defined and hypoechoic solid mass within the subcutaneous fat tissue in the areolar area. Mass was isointense compared to muscle and hypointense compared to fat tissue on TIW and T2W MR images. Excisional biopsy was applied to the mass. The diagnosis of gynecomastia and neurofibroma was made on the basis of histopathological and immunohistochemical findings.