Calciphylaxis of the temporal artery masquerading as temporal arteritis

We describe a case of a 75‐year‐old man with diabetes type II and end‐stage renal disease, presenting with a one‐month history of blurring of vision in the left eye. Fundus exam showed pale and swollen optic nerve in the left eye, and temporal artery biopsy showed diffuse and extensive calcification...

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Bibliographic Details
Published in:	Clinical & experimental ophthalmology Vol. 38; no. 5; pp. 511 - 513
Main Authors:	Awwad, Shady T, Ghosn, Samer, Hogan, R Nick
Format:	Journal Article
Language:	English
Published:	Melbourne, Australia Blackwell Publishing Asia 01-07-2010
Subjects:	Aged Biopsy Calciphylaxis - diagnosis Calciphylaxis - pathology Diagnosis, Differential giant cell arteritis Giant Cell Arteritis - diagnosis histology Humans Male optic neuritis Subcutaneous Fat - pathology Temporal Arteries - pathology
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Summary:	We describe a case of a 75‐year‐old man with diabetes type II and end‐stage renal disease, presenting with a one‐month history of blurring of vision in the left eye. Fundus exam showed pale and swollen optic nerve in the left eye, and temporal artery biopsy showed diffuse and extensive calcification at the internal elastic lamina and media. Biopsy of dusky erythematous lesions over the calves revealed the diagnosis of calciphylaxis. The temporal artery calcific lesions should hence be differentiated from the less extensive atherosclerotic changes, which mainly affect the media of the artery, as it is crucial to suspect this life‐threatening diagnosis in patients at risk.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3 ObjectType-Article-1 ObjectType-Feature-2
ISSN:	1442-6404 1442-9071
DOI:	10.1111/j.1442-9071.2010.02281.x