Primary intracranial basaloid squamous cell carcinoma: an enigma

Primary intracranial basaloid squamous cell carcinoma: an enigma

Primary intracranial squamous cell carcinoma is extremely rare, with most cases arising from malignant transformation of dysembryogenetic lesions such as epidermoid and dermoid cysts. Intracranial squamous cell neoplasm arising de novo is even rarer and has been reported in only four patients to dat...

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Bibliographic Details
Published in:Neurologia i neurochirurgia polska Vol. 46; no. 5; p. 489
Main Authors: Mallick, Supriya, Biswas, Ahitagni, Kumar, Narender, Chand Sharma, Mehar, Kumar, Rakesh, Mohan Reddy, Rama, Kumar Julka, Pramod, Kishore Rath, Goura
Format: Journal Article
Language:English
Published: Poland 01-09-2012
Subjects:
Adenocarcinoma - pathology
Adult
Brain Neoplasms - diagnosis
Brain Neoplasms - pathology
Brain Neoplasms - radiotherapy
Brain Neoplasms - surgery
Carcinoma, Squamous Cell - diagnosis
Carcinoma, Squamous Cell - pathology
Carcinoma, Squamous Cell - radiotherapy
Carcinoma, Squamous Cell - surgery
Diagnosis, Differential
Female
Humans
Radiotherapy, Adjuvant
Remission Induction
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Summary:Primary intracranial squamous cell carcinoma is extremely rare, with most cases arising from malignant transformation of dysembryogenetic lesions such as epidermoid and dermoid cysts. Intracranial squamous cell neoplasm arising de novo is even rarer and has been reported in only four patients to date. We herein describe a case of primary intracranial squamous cell carcinoma arising de novo in the right frontal lobe in a 35-year-old woman treated with a combination of surgery and postoperative conformal radiation. We have also shed light on the biology and the therapeutic options of this enigmatic tumour.
ISSN:0028-3843
DOI:10.5114/ninp.2012.31361