Priming with Chlamydia trachomatis Major Outer Membrane Protein (MOMP) DNA followed by MOMP ISCOM Boosting Enhances Protection and Is Associated with Increased Immunoglobulin A and Th1 Cellular Immune Responses

• Published in: Infection and Immunity Vol. 68; no. 6; pp. 3074 - 3078
• Main Authors: Dong-Ji, Zhang, Yang, Xi, Shen, Caixia, Lu, Hong, Murdin, Andrew, Brunham, Robert C.
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01-06-2000
• Subjects: AIDS/HIV; Animals; Antibodies, Bacterial - blood; Bacterial Outer Membrane Proteins - immunology; Bacterial Vaccines - therapeutic use; Bacteriology; Biological and medical sciences; Chlamydia Infections - prevention & control; Chlamydia trachomatis; Chlamydia trachomatis - immunology; Female; Fundamental and applied biological sciences. Psychology; Hypersensitivity, Delayed; Immunity, Cellular; Immunization, Secondary; Immunoglobulin A - blood; Interferon-gamma - biosynthesis; Interleukin-10 - biosynthesis; ISCOMs - immunology; Major outer membrane protein; Mice; Mice, Inbred BALB C; Microbial Immunity and Vaccines; Microbiology; Pneumonia - prevention & control; Porins; Spleen - cytology; Spleen - immunology; Th1 Cells - immunology; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies; IgA; Membrane protein; Helper cell; Chlamydia trachomatis; Cellular immunity; Local immunity; Chlamydiales; Bacteria; Chlamydiosis; Immunostimulating complex; Immunoprotection; Immunoglobulins; Immunostimulation; Immune response; Chlamydiaceae; Rodentia; Vaccine; External membrane; Infection; Vertebrata; Mammalia; Immunogenicity; Mouse; Animal; Bacteriosis
• ISSN: 0019-9567; 1098-5522
• DOI: 10.1128/IAI.68.6.3074-3078.2000

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