The Blood−Brain Barrier in Neuroimmune Interactions and Pathological Processes

The Blood−Brain Barrier in Neuroimmune Interactions and Pathological Processes

The blood–brain barrier (BBB) is a kind of filter, highly selective in relation to various types of substances. The BBB supports the immune status of the brain and is an important regulator of neuroimmune interactions. Some of the molecular and cellular features of the BBB, as well as the five main...

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Bibliographic Details
Published in:Herald of the Russian Academy of Sciences Vol. 92; no. 5; pp. 590 - 599
Main Authors: Dyatlova, A. S., Novikova, N. S., Yushkov, B. G., Korneva, E. A., Chereshnev, V. A.
Format: Journal Article
Language:English
Published: Moscow Pleiades Publishing 2022
Springer Nature B.V
Subjects:
Blood-brain barrier
Chemistry/Food Science
COVID-19
Earth and Environmental Science
Earth Sciences
Engineering
Environment
Immune status
Life Sciences
Multiple sclerosis
Review
Social Sciences
Viral diseases
COVID-19
blood−brain barrier
neurodegenerative diseases
neuroimmune interactions
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Summary:The blood–brain barrier (BBB) is a kind of filter, highly selective in relation to various types of substances. The BBB supports the immune status of the brain and is an important regulator of neuroimmune interactions. Some of the molecular and cellular features of the BBB, as well as the five main pathways of neuroimmune communication mediated by the BBB, are analyzed in this article. The functions of the BBB in neuroimmune interactions in various diseases are discussed: multiple sclerosis and Alzheimer’s and Parkinson’s diseases. The latest data on BBB dysfunction in COVID-19 coronavirus infection caused by the SARS-CoV-2 virus are considered.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:1019-3316
1555-6492
DOI:10.1134/S1019331622050100