Indonesian native goats (Capra hircus) reveal highest genetic frequency of mitochondrial DNA haplogroup B in the world

• Published in: Animal science journal Vol. 91; no. 1; pp. e13485 - n/a
• Main Authors: Mannen, Hideyuki, Iso, Kenta, Kawaguchi, Fuki, Sasazaki, Shinji, Yonezawa, Takahiro, Dagong, Muhammad Ihsan Andi, Bugiwati, Sri Rachma Aprilita
• Format: Journal Article
• Language: English
• Published: Australia Blackwell Publishing Ltd 01-01-2020
• Subjects: Animals; Breeding; Capra hircus; Deoxyribonucleic acid; DNA; DNA, Mitochondrial - genetics; Gene Frequency - genetics; genetic diversity; Genetic Introgression - genetics; Goats; Goats - genetics; haplogroup B; Haplotypes; Haplotypes - genetics; Indonesia; Mitochondrial DNA; Phylogeny; Sequence Analysis, DNA; Indonesia; Southeast Asia; genetic diversity; haplogroup B; mitochondrial DNA; goats; Indonesia
• ISSN: 1344-3941; 1740-0929
• DOI: 10.1111/asj.13485

The objective of this study was to determine mtDNA sequences of the 481 bp HV1 region from two Indonesian native goat breeds, Kacang and Marica, to confirm the phylogeographic distribution of caprine haplogroup B in Southeast Asia. Based on these sequences, 12 haplotypes were observed and categorized into the predominant haplogroup B and minority haplogroup A, indicating that Indonesian native goats present the highest frequency (0.950) of the haplogroup B in the world. These results strongly emphasize previous observations of the haplogroup B frequencies tending to increase southeastward in Southeast Asia. Additionally, this suggests that goats primary bred into Southeast Asia might predominantly carry haplogroup B. This could essentially contribute to the understanding of the origin, propagation route and/or introgression history of Southeast Asian goats.