High-Separation Performance of Chromatographic Capillaries Coated with MOF-5 by the Controlled SBU Approach

• Published in: Chemistry : a European journal Vol. 17; no. 39; pp. 10958 - 10964
• Main Authors: Münch, Alexander S., Seidel, Jürgen, Obst, Anja, Weber, Edwin, Mertens, Florian O. R. L.
• Format: Journal Article
• Language: English
• Published: Weinheim WILEY-VCH Verlag 19-09-2011; WILEY‐VCH Verlag; Wiley Subscription Services, Inc
• Subjects: Chromatography; gas chromatography; kinetics; metal-organic frameworks; self-assembly; supramolecular chemistry
• ISSN: 0947-6539; 1521-3765
• DOI: 10.1002/chem.201100642

Recently developed MOF surface‐coating techniques, the controlled SBU approach (CSA) for the generation of MOF‐5, and the use of self‐assembled monolayers have been combined to generate a wall‐bonded, crosslinked stationary phase for gas chromatographic capillary columns displaying excellent performance in the separation of natural gas components. The chromatographic performance of this new type of column has been compared to the state‐of‐the‐art solution for this separation problem, namely a coated silica column of the porous layer open tubular (PLOT) type. Chromatographic parameters such as separation, resolution, and tailing factors, as well as plate numbers and heights in the case of isothermal operation, have been determined. Kinetic and thermodynamic parameters characterizing the analyte–stationary phase interaction have been determined for various C1–C4 analytes.
Based on special surface preparation techniques using self‐assembled monolayers and the controlled SBU approach (CSA) for the deposition of metal–organic frameworks, MOF‐CSA‐based coatings in capillary columns for gas chromatography have been produced (see graphic, orange trace: MOF‐based, blue trace: commercially available PLOT column).