Zika Virus Disease and Pregnancy Outcomes in Colombia

• Published in: The New England journal of medicine Vol. 383; no. 6; pp. 537 - 545
• Main Authors: Ospina, Martha L, Tong, Van T, Gonzalez, Maritza, Valencia, Diana, Mercado, Marcela, Gilboa, Suzanne M, Rodriguez, Andrea J, Tinker, Sarah C, Rico, Angelica, Winfield, Christina M, Pardo, Lissethe, Thomas, Jennifer D, Avila, Greace, Villanueva, Julie M, Gomez, Sara, Jamieson, Denise J, Prieto, Franklyn, Meaney-Delman, Dana, Pacheco, Oscar, Honein, Margaret A
• Format: Journal Article
• Language: English
• Published: United States Massachusetts Medical Society 06-08-2020
• Subjects: Adolescent; Adult; Babies; Birth defects; Brain - abnormalities; Colombia - epidemiology; Congenital defects; Disease Outbreaks; Epidemics; Eye Abnormalities - epidemiology; Female; Fetal Diseases - epidemiology; Fetus - abnormalities; Fetuses; Geography, Medical; Gestational age; Health surveillance; Humans; Incidence; Infant, Newborn; Infants; Infections; Laboratories; Low birth weight; Male; Microcephaly; Microcephaly - epidemiology; Multiple births; Nervous system; Outbreaks; Poisson Distribution; Polymerase chain reaction; Pregnancy; Pregnancy Complications, Infectious - epidemiology; Pregnancy Outcome; Premature birth; Prevalence; Pruritus; Public health; Real-Time Polymerase Chain Reaction; Ribonucleic acid; RNA; RNA viruses; RNA, Viral - blood; Womens health; Young Adult; Zika virus; Zika Virus - genetics; Zika Virus - isolation & purification; Zika Virus Infection - complications; Zika Virus Infection - epidemiology; Colombia
• ISSN: 0028-4793; 1533-4406
• DOI: 10.1056/NEJMoa1911023

In an epidemiologic study of the Zika virus outbreak in Columbia in 2015 and 2016, brain or eye defects were diagnosed in 93 of 5673 infants or fetuses (2%) carried by women with laboratory-confirmed Zika virus disease.