Efficacy of pars plana vitrectomy combined with internal limiting membrane peeling and gas tamponade for treating myopic foveoschisis: a meta-analysis

• Published in: BMC ophthalmology Vol. 24; no. 1; pp. 293 - 14
• Main Authors: Song, Shuqi, He, Guanglun, Huang, Di, Li, Xiaojuan, Wu, Zhenzhen, Sun, Yongfeng
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 18-07-2024; BioMed Central; BMC
• Subjects: Acuity; Basement Membrane - surgery; Cataracts; Cohort analysis; Complications; Endotamponade - methods; Evidence-based medicine; Gas tamponade; Humans; Iatrogenesis; Information management; Internal limiting membrane peeling; Intervention; Macular foveoschisis; Meta-analysis; Myopia; Myopia - physiopathology; Myopia - surgery; Myopia, Degenerative - complications; Myopia, Degenerative - physiopathology; Myopia, Degenerative - surgery; Pars plana vitrectomy; Pay-per-view television; Postoperative; Retinoschisis - surgery; Statistical analysis; Surgeons; Surgery; Tamponade; Visual acuity; Visual Acuity - physiology; Vitrectomy - methods; Internal limiting membrane peeling; Pars plana vitrectomy; Gas tamponade; Macular foveoschisis
• ISSN: 1471-2415; 1471-2415
• DOI: 10.1186/s12886-024-03534-2

This study aimed to evaluate and explore the efficacy of pars plana vitrectomy (PPV) combined with internal limiting membrane (ILM) peeling and gas tamponade in treating myopic foveoschisis (MF) through a meta-analysis.
Systematic searches were conducted on the PubMed, Web of Science and National Library of Medicine (NLM) English-language databases and the China National Knowledge Infrastructure (CNKI) and Wanfang Chinese-language databases. The primary outcome measures were postoperative best-corrected visual acuity (BCVA) and central foveal thickness (CFT), with the secondary outcome being the postoperative complication rate. Data analysis was performed using RevMan5.3 software.
A total of 10 studies involving 234 eyes were included. The meta-analysis results showed the following: (1) The average postoperative BCVA improved compared with preoperative levels, with an average improvement in the logarithm of the minimum angle of resolution of 0.40, a statistically significant difference (95% CI: -0.44, - 0.20, p < 0.001); (2) the rate of postoperative BCVA improvement was 77% (95% CI: 65%, 90%, p < 0.001); (3) the postoperative CFT significantly decreased by an average of 385.92 μm, a statistically significant difference (95% CI: -437.85, - 333.98, p < 0.001); (4) the postoperative macular retinal complete reattachment rate was 90% (95% CI: 83%, 97%, p < 0.001); (5) the most common postoperative complication was a cataract, with an incidence of 55.9%.
Using PPV combined with ILM peeling and gas tamponade to treat MF is reliable.