Editorial Expression of Concern: Splenic T1-mapping: a novel quantitative method for assessing adenosine stress adequacy for cardiovascular magnetic resonance

• Published in: Journal of cardiovascular magnetic resonance Vol. 25; no. 1; p. 27
• Main Authors: Liu, Alexander, Wijesurendra, Rohan S., Ariga, Rina, Mahmod, Masliza, Levelt, Eylem, Greiser, Andreas, Petrou, Mario, Krasopoulos, George, Forfar, John C., Kharbanda, Rajesh K., Channon, Keith M., Neubauer, Stefan, Piechnik, Stefan K., Ferreira, Vanessa M.
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 25-05-2023; BioMed Central Ltd; BioMed Central; Elsevier
• Subjects: Adenosine; Adequacy; Bibliometrics; Editorials; Magnetic resonance; Medicine; Reproducibility; Spleen; United Kingdom > UK
• ISSN: 1097-6647; 1532-429X
• DOI: 10.1186/s12968-023-00935-y

Thorough reanalysis of available data found that the strong links between the splenic signal intensity change and delta spleen T1, and the ability of delta spleen T1 to predict the splenic switch-off sign, could not be independently reproduced, although the general observations reported in Table 2 (that the spleen T1 decreases significantly in response to Adenosine) and inter-observer reproducibility of delta spleen T1 could be reproduced. [...]of the information available, the Editor-in-Chief advises readers to interpret the results of this publication with due caution. Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. Thorough reanalysis of available data found that the strong links between the splenic signal intensity change and delta spleen T1, and the ability of delta spleen T1 to predict the splenic switch-off sign, could not be independently reproduced, although the general observations reported in Table 2 (that the spleen T1 decreases significantly in response to Adenosine) and inter-observer reproducibility of delta spleen T1 could be reproduced. [...]of the information available, the Editor-in-Chief advises readers to interpret the results of this publication with due caution.