Presynaptic imaging techniques

Presynaptic imaging techniques

Understanding the detailed molecular events that support chemical synaptic transmission requires high-resolution methods that provide quantitative information combined with molecular specificity. In recent years, many new technological approaches, including genetically encoded fluorescent indicators...

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Bibliographic Details
Published in:Current Opinion in Neurobiology Vol. 11; no. 5; pp. 544 - 549
Main Author: Ryan, Timothy A
Format: Book Review Journal Article
Language:English
Published: England Elsevier Ltd 01-10-2001
Subjects:
Animals
Fluorescent Dyes - analysis
FM 1-43
GFP
Humans
Image Processing, Computer-Assisted - methods
membrane traffic
Neurons - chemistry
Neurons - physiology
pHluorin
Presynaptic Terminals - chemistry
Presynaptic Terminals - physiology
Pyridinium Compounds - analysis
Quaternary Ammonium Compounds - analysis
synapse
Synaptic Transmission - physiology
Synaptic Vesicles - chemistry
Synaptic Vesicles - physiology
vesicles
GFP
Neuroscience
Techniques & Methods
FM 1-43
Cell biology
Pharmacology
Physiology
synapse
pHluorin
membrane traffic
vesicles
Online Access:Get full text
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Description
Summary:Understanding the detailed molecular events that support chemical synaptic transmission requires high-resolution methods that provide quantitative information combined with molecular specificity. In recent years, many new technological approaches, including genetically encoded fluorescent indicators, ultra-thin sectioning, and live-cell imaging have been brought to bear on understanding the cell biology and physiology of presynaptic terminals.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
ObjectType-Review-3
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ObjectType-Review-1
ISSN:0959-4388
1873-6882
DOI:10.1016/S0959-4388(00)00247-6