Spatial correction improves accuracy of catheter positioning during ablation of premature ventricular contractions: differences between ventricular outflow tracts and other localizations

• Published in: BMC cardiovascular disorders Vol. 22; no. 1; p. 312
• Main Authors: Nies, M, Schleberger, R, Dinshaw, L, Klatt, N, Muenkler, P, Jungen, C, Rottner, L, Lemoine, M D, Reißmann, B, Rillig, A, Metzner, A, Kirchhof, P, Meyer, C
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 13-07-2022; BioMed Central; BMC
• Subjects: Ablation; Activation mapping; Admixture mapping; Aged; Arrhythmia; Cardiomyopathy; Cardiovascular disease; Care and treatment; Catheter ablation; Catheter Ablation - adverse effects; Catheter Ablation - methods; Catheters; Coronary vessels; Diagnosis; Ejection fraction; Female; Heart Ventricles; Humans; Hybrid mapping; Localization; Male; Mapping; Methods; Middle Aged; Morphology; Myocardium; Patients; Premature ventricular contractions; Risk factors; Sarcoidosis; Sinuses; Software; Treatment Outcome; Variables; Ventricle; Ventricular Premature Complexes - diagnosis; Ventricular Premature Complexes - surgery; Germany; Premature ventricular contractions; Activation mapping; Catheter ablation; Hybrid mapping
• ISSN: 1471-2261; 1471-2261
• DOI: 10.1186/s12872-022-02741-3

Hybrid activation mapping is a novel tool to correct for spatial displacement of the mapping catheter due to asymmetrical contraction of myocardium during premature ventricular contractions (PVC). The aim of this study is to describe and improve our understanding of spatial displacement during PVC mapping as well as options for correction using hybrid activation mapping.
We analyzed 5798 hybrid mapping points in 40 acquired hybrid maps of 22 consecutive patients (age 63 ± 16 years, 45% female) treated for premature ventricular contractions (PVCs). Median PVC-coupling interval was 552 ms (IQR 83 ms). Spatial displacement was determined by measuring the dislocation of the catheter tip during PVC compared to the preceding sinus beat. Mean spatial displacement was 3.8 ± 1.5 mm for all maps. The displacement was 1.3 ± 0.4 mm larger for PVCs with non-outflow-tract origin compared to PVCs originating from the ventricular outflow tracts (RVOT/LVOT; p = 0.045). Demographic parameters, PVC-coupling-interval and chamber of origin had no significant influence on the extent of spatial displacement.
Ectopic activation of the ventricular myocardium during PVCs results in spatial displacement of mapping points that is significantly larger for PVCs with non-outflow-tract origin. The correction for spatial displacement may improve accuracy of radiofrequency current (RFC)-application in catheter ablation of PVCs.