Release and transportation of Hedgehog molecules

Highlights ► Lipidated Hedgehog proteins spread in the hydrophilic extracellular space. ► Different Hedgehog carriers are involved in short and long range transportation. ► Carriers for Hedgehog work in parallel in the same cells.

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Bibliographic Details
Published in:	Current opinion in cell biology Vol. 24; no. 2; pp. 173 - 180
Main Author:	Thérond, Pascal P
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01-04-2012 Elsevier
Subjects:	Animals Carrier Proteins Carrier Proteins - isolation & purification Cell Membrane Cell Membrane - metabolism Cholesterol Cholesterol - metabolism Development Biology Extracellular Space Extracellular Space - chemistry Extracellular Space - metabolism Hedgehog Proteins Hedgehog Proteins - metabolism Internal Medicine Life Sciences Morphogenesis Palmitic Acid Palmitic Acid - metabolism Protein Processing, Post-Translational Protein Transport
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Description
Summary:	Highlights ► Lipidated Hedgehog proteins spread in the hydrophilic extracellular space. ► Different Hedgehog carriers are involved in short and long range transportation. ► Carriers for Hedgehog work in parallel in the same cells.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	0955-0674 1879-0410
DOI:	10.1016/j.ceb.2012.02.001