Clinical and Histological Evaluation of Ceramic Matrix in a Collagen Carrier for Socket Preservation in Humans

• Published in: Implant dentistry Vol. 25; no. 1; pp. 149 - 154
• Main Author: El-Chaar, Edgard S
• Format: Journal Article
• Language: English
• Published: United States 01-02-2016
• Subjects: Adult; Aged; Aged, 80 and over; Alveolar Ridge Augmentation - methods; Ceramics - therapeutic use; Collagen - therapeutic use; Dental Implantation, Endosseous - methods; Dental Implants, Single-Tooth; Dentistry; Durapatite - therapeutic use; Female; Humans; Male; Middle Aged; Tooth Socket - drug effects; Tooth Socket - pathology
• ISSN: 1056-6163; 1538-2982
• DOI: 10.1097/id.0000000000000362

A case series was used to evaluate the efficacy and predictability of a ceramic matrix in a putty-like collagen carrier in immediate extraction sockets.
A single failing tooth was atraumatically extracted from each of 10 subjects. The sockets were debrided and grafted with ceramic matrix in a putty-like collagen carrier (15% hydroxyapatite, 85% β-tricalcium phosphate complex). A bovine pericardium membrane was draped over the graft site and a tension-free primary closure was obtained. After 6 months of healing, a trephine biopsy was taken from the center of each graft and a dental implant was placed. Two subjects were withdrawn from the study and were considered treatment failures. One of them moved to another state and the second exhibited delayed healing that required debridement of the grafting material from the socket.
After 6 months follow-up, there was a mean reduction of ridge width of 1.667 mm and mean reduction of ridge height of 0.483 mm after graft healing and integration. Over a 24-month follow-up, mean new bone fill was 40.25% and implant osseointegration was 100%.
Ceramic matrix in a putty-like collagen carrier maintained ridge dimensions and, despite ongoing bone turnover, produced adequate mineralized tissue that enabled implant placement at 6 months.