Effect of tranexamic acid on rebleeding after subarachnoid hemorrhage: a double-blind controlled clinical trial

In a double-blind controlled clinical trial on 51 patients with subarachnoid hemorrhage, tranexamic acid, 4 gm per day for ten consecutive days, did not favorably affect the outcome. Neither mortality nor rebleeding rates were improved after a follow-up of three months.

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Bibliographic Details
Published in:	Annals of neurology Vol. 2; no. 3; p. 238
Main Authors:	van Rossum, J, Wintzen, A R, Endtz, L J, Schoen, J H, de Jonge, H
Format:	Journal Article
Language:	English
Published:	United States 01-09-1977
Subjects:	Aged Cerebral Angiography Clinical Trials as Topic Cyclohexanecarboxylic Acids - therapeutic use Double-Blind Method Humans Intracranial Aneurysm - diagnostic imaging Middle Aged Prognosis Recurrence Subarachnoid Hemorrhage - diagnostic imaging Subarachnoid Hemorrhage - drug therapy Subarachnoid Hemorrhage - mortality Tranexamic Acid - therapeutic use
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Description
Summary:	In a double-blind controlled clinical trial on 51 patients with subarachnoid hemorrhage, tranexamic acid, 4 gm per day for ten consecutive days, did not favorably affect the outcome. Neither mortality nor rebleeding rates were improved after a follow-up of three months.
ISSN:	0364-5134
DOI:	10.1002/ana.410020311