Xanthogranulomatous pancreatitis combined with intraductal papillary mucinous carcinoma in situ

• Published in: Journal of Korean medical science Vol. 25; no. 12; pp. 1814 - 1817
• Main Authors: Kim, Yo Na, Park, Shin Young, Kim, Young Kon, Moon, Woo Sung
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Academy of Medical Sciences 01-12-2010; 대한의학회
• Subjects: Adenocarcinoma, Mucinous - diagnosis; Adenocarcinoma, Mucinous - pathology; Adenocarcinoma, Mucinous - surgery; Aged; Carcinoma in Situ - diagnosis; Carcinoma in Situ - pathology; Carcinoma in Situ - surgery; Carcinoma, Pancreatic Ductal - diagnosis; Carcinoma, Pancreatic Ductal - pathology; Carcinoma, Pancreatic Ductal - surgery; Carcinoma, Papillary - diagnosis; Carcinoma, Papillary - pathology; Carcinoma, Papillary - surgery; Case Report; Diagnosis, Differential; Female; Granuloma - complications; Granuloma - diagnosis; Humans; Magnetic Resonance Imaging; Pancreatic Neoplasms - diagnosis; Pancreatic Neoplasms - pathology; Pancreatic Neoplasms - surgery; Pancreaticoduodenectomy; Pancreatitis - complications; Pancreatitis - diagnosis; Tomography, X-Ray Computed; Xanthomatosis - complications; Xanthomatosis - diagnosis; 의학일반; Cystic Tumor; Pancreas; Xanthogranulomatous Inflammation
• ISSN: 1011-8934; 1598-6357
• DOI: 10.3346/jkms.2010.25.12.1814

Xanthogranulomatous lesion is a rare condition in which lipid-laden histiocytes are deposited at various locations in the body. Xanthogranulomatous pancreatitis (XGP) associated with an intraductal papillary mucinous tumor (IPMT) is extremely rare. In this study, we described a case of XGP associated with IPMT and include a review of the literature. A pancreatic cystic mass was detected in a 72-yr-old woman by abdominal computed tomography. Pylorus-preserving pancreaticoduodenectomy was performed and diagnosis of XGP combined with intraductal papillary mucinous carcinoma in situ was made. After 13 months of follow-up, the patient is in good health without any evidence of tumor recurrence. Although XGP associated with IPMT is rare, we suggest that such cases should be brought to the attention of clinical investigators, as it may produce clinical features that mimic pancreatic cancer.