An open trial of topical tacrolimus for erosive oral lichen planus

Erosive oral lichen planus is a chronic, painful disease that is frequently refractory to treatment. We describe 6 patients with erosive oral lichen planus, not responsive to topical steroids, who showed substantial improvement with the use of topical tacrolimus ointment 0.1%. This medication was we...

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Bibliographic Details
Published in:	Journal of the American Academy of Dermatology Vol. 47; no. 4; pp. 617 - 620
Main Authors:	Morrison, Lynne, Kratochvil, F.James, Gorman, Annalisa
Format:	Journal Article
Language:	English
Published:	New York, NY Mosby, Inc 01-10-2002 Elsevier
Subjects:	Administration, Topical Adult Biological and medical sciences Ent. Stomatology Female Humans Immunosuppressive Agents - administration & dosage Immunosuppressive Agents - blood Immunosuppressive Agents - therapeutic use Lichen Planus, Oral - blood Lichen Planus, Oral - drug therapy Male Medical sciences Pharmacology. Drug treatments Tacrolimus - administration & dosage Tacrolimus - blood Tacrolimus - therapeutic use Treatment Outcome Human Stomatology Lactone Lichen planus Macrocycle Immunomodulator Oral cavity Local administration Chemotherapy Treatment Tacrolimus Clinical trial Oral cavity disease Erosion
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Summary:	Erosive oral lichen planus is a chronic, painful disease that is frequently refractory to treatment. We describe 6 patients with erosive oral lichen planus, not responsive to topical steroids, who showed substantial improvement with the use of topical tacrolimus ointment 0.1%. This medication was well tolerated and appears to be effective in controlling erosive oral lichen planus. (J Am Acad Dermatol 2002;47:617-20.)
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23
ISSN:	0190-9622 1097-6787
DOI:	10.1067/mjd.2002.126275