Group A rotavirus genotypes in Germany during 2005/2006

• Published in: Archives of virology Vol. 152; no. 9; pp. 1743 - 1749
• Main Authors: Marques, A. Mas, Diedrich, S, Huth, C, Schreier, E
• Format: Journal Article
• Language: English
• Published: Wien Vienna : Springer-Verlag 01-09-2007; New York, NY Springer; Springer Nature B.V
• Subjects: Antigens; Biological and medical sciences; Epidemiology; Feces - virology; Fundamental and applied biological sciences. Psychology; Gastroenteritis; Gastroenteritis - epidemiology; Gastroenteritis - virology; Genomes; Genotype; Genotype & phenotype; Genotypes; Germany - epidemiology; Group a rotavirus; Human rotavirus; Humans; Infections; Microbiology; Miscellaneous; Mutation; Pathogens; Rotavirus; Rotavirus - classification; Rotavirus - genetics; Rotavirus - isolation & purification; Rotavirus Infections - epidemiology; Rotavirus Infections - virology; Vaccines; Virology; Viruses; Zoonoses; Europe; Germany; Virus; Genotype; Rotavirus; Reoviridae
• ISSN: 0304-8608; 1432-8798
• DOI: 10.1007/s00705-007-0998-x

During the 2005/2006 winter season a total of 802 group A positive rotavirus specimens of patients from different regions throughout Germany were genotyped. Amplicons from a one-tube RT-PCR were typed by analysis of their (type-specific) size using type-specific primers, fluorescent consensus primers and a capillary sequencer for detection. While G1P[8] was predominant (45.8%), G9P[8] has emerged as the second most frequent genotype combination (37.7%). The distribution of genotypes was heterogeneous, regional frequencies regarding G1 and G9 were ranging from 15.0 to 89.3% and from 7.1 to 67.7%, respectively. Furthermore, a few human rotavirus G10P[6] and G10P[8] infections were observed.