Neuronal specification: Generating diversity in the spinal cord

Neuronal specification: Generating diversity in the spinal cord

Graded Sonic hedgehog signaling may generate neuronal diversity in the ventral spinal cord in two steps: the creation of a generic population of ventral progenitors, followed by the Pax6-dependent generation of distinct subpopulations within these ventral progenitors.

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Bibliographic Details
Published in:Current biology Vol. 7; no. 11; pp. R701 - R704
Main Author: Pituello, Fabienne
Format: Journal Article
Language:English
Published: England Elsevier Inc 01-11-1997
Subjects:
Animals
Cell Differentiation - genetics
Hedgehog Proteins
Models, Neurological
Neurons - cytology
Neurons - physiology
Proteins - genetics
Signal Transduction - genetics
Spinal Cord - cytology
Spinal Cord - physiology
Trans-Activators
Online Access:Get full text
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Description
Summary:Graded Sonic hedgehog signaling may generate neuronal diversity in the ventral spinal cord in two steps: the creation of a generic population of ventral progenitors, followed by the Pax6-dependent generation of distinct subpopulations within these ventral progenitors.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ObjectType-Review-3
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ISSN:0960-9822
1879-0445
DOI:10.1016/S0960-9822(06)00360-5