Fast track anesthesia for liver transplantation: Review of the current practice

Historically,patients undergoing liver transplantation were left intubated and extubated in the intensive care unit(ICU)after a period of recovery.Proponents of this practice argued that these patients were critically ill andneed time to be properly optimized from a physiological and pain standpoint...

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Published in:World journal of hepatology Vol. 7; no. 20; pp. 2303 - 2308
Main Authors: Aniskevich, Stephen, Pai, Sher-Lu
Format: Journal Article
Language:English
Published: United States Baishideng Publishing Group Inc 18-09-2015
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Summary:Historically,patients undergoing liver transplantation were left intubated and extubated in the intensive care unit(ICU)after a period of recovery.Proponents of this practice argued that these patients were critically ill andneed time to be properly optimized from a physiological and pain standpoint prior to extubation.Recently,there has been a growing movement toward early extubation in transplant centers worldwide.Initially fueled by research into early extubation following cardiac surgery,extubation in the operating room or soon after arrival to the ICU,has been shown to be safe with proper patient selection.Additionally,as experience at determining appropriate candidates has improved,some institutions have developed systems to allow select patients to bypass the ICU entirely and be admitted to the surgical ward after transplant.We discuss the history of early extubation and the arguments in favor and against fast track anesthesia.We also described our practice of fast track anesthesia at Mayo Clinic Florida,in which,we extubate approximately 60%of our patients in the operating room and send them to the surgical ward after a period of time in the post anesthesia recovery unit.
Bibliography:Historically,patients undergoing liver transplantation were left intubated and extubated in the intensive care unit(ICU)after a period of recovery.Proponents of this practice argued that these patients were critically ill andneed time to be properly optimized from a physiological and pain standpoint prior to extubation.Recently,there has been a growing movement toward early extubation in transplant centers worldwide.Initially fueled by research into early extubation following cardiac surgery,extubation in the operating room or soon after arrival to the ICU,has been shown to be safe with proper patient selection.Additionally,as experience at determining appropriate candidates has improved,some institutions have developed systems to allow select patients to bypass the ICU entirely and be admitted to the surgical ward after transplant.We discuss the history of early extubation and the arguments in favor and against fast track anesthesia.We also described our practice of fast track anesthesia at Mayo Clinic Florida,in which,we extubate approximately 60%of our patients in the operating room and send them to the surgical ward after a period of time in the post anesthesia recovery unit.
Stephen Aniskevich;Sher-Lu Pai;Department of Anes- thesiology, Division of Hepatobiliary and Abdominal Organ Transplant, Mayo Clinic Florida
Liver transplant;Fast track anesthesia;Early extub
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Correspondence to: Stephen Aniskevich, MD, Department of Anesthesiology, Division of Hepatobiliary and Abdominal Organ Transplant, Mayo Clinic Florida, 4500 San Pablo Rd, Jacksonville, FL 32224, United States. stephen2@mayo.edu
Telephone: +1-904-9533328 Fax: +1-904-9563332
Author contributions: Aniskevich S and Pai SL contributed to the writing and editing of this manuscript.
ISSN:1948-5182
1948-5182
DOI:10.4254/wjh.v7.i20.2303