Biodegradable stents in gastrointestinal endoscopy

Biodegradable stents in gastrointestinal endoscopy

Biodegradable stents(BDSs)are an attractive option to avoid ongoing dilation or surgery in patients with benign stenoses of the small and large intestines.The experience with the currently the only BDS for endoscopic placement,made of Poly-dioxanone,have shown promising results.However some aspects...

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Bibliographic Details
Published in:World journal of gastroenterology : WJG Vol. 20; no. 9; pp. 2212 - 2217
Main Authors: Lorenzo-Zúñiga, Vicente, Moreno-de-Vega, Vicente, Marín, Ingrid, Boix, Jaume
Format: Journal Article
Language:English
Published: United States Baishideng Publishing Group Co., Limited 07-03-2014
Subjects:
Absorbable Implants
Biodegradable
Constriction, Pathologic
Endoscop
Endoscopy
Endoscopy, Gastrointestinal - adverse effects
Endoscopy, Gastrointestinal - instrumentation
Gastrointestinal Diseases - diagnosis
Gastrointestinal Diseases - therapy
Humans
Prosthesis Design
Stents
Strictures
Topic Highlight
Treatment Outcome
Biodegradable stents
Endoscopy
Strictures
Endoscopic placement
Stenoses
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Description
Summary:Biodegradable stents(BDSs)are an attractive option to avoid ongoing dilation or surgery in patients with benign stenoses of the small and large intestines.The experience with the currently the only BDS for endoscopic placement,made of Poly-dioxanone,have shown promising results.However some aspects should be improved as are the fact that BDSs lose their radial force over time due to the degradable material,and that can cause stent-induced mucosal or parenchymal injury.This complication rate and modest clinical efficacy has to be carefully considered in individual patients prior to placement of BDSs.Otherwise,the price of these stents therefore it is nowadays an important limitation.
Bibliography:Vicente Lorenzo-Zú?iga;Vicente Moreno-de-Vega;Ingrid Marín;Jaume Boix;Endoscopy Unit, Department of Gastroenterology, Hospital Universitari Germans Trias i Pujol, 08916 Badalona, Spain;Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), 08916 Badalona, Spain
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
Author contributions: Lorenzo-Zúñiga V was involved in editing the manuscript and wrote the manuscript; Moreno-de-Vega V, Marín I and Boix J revised the manuscript.
Telephone: +34-93-4978866 Fax: +34-93-4978866
Correspondence to: Vicente Lorenzo-Zúñiga, MD, PhD, Endoscopy Unit, Department of Gastroenterology, Hospital Universitari Germans Trias i Pujol, Carretera del Canyet s/n. 08916 Badalona, Spain. vlorenzo.germanstrias@gencat.cat
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v20.i9.2212