Treatment of spinocerebellar ataxia with buspirone
Abstract Preliminary data suggest potential benefit of 5-HT receptor agonists in the treatment of ataxias. We studied the effects of buspirone in a cohort of twenty patients with spinocerebellar ataxia (SCA). Twenty patients were treated in this double-blind, placebo controlled, cross-over trial wit...
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Published in: | Journal of the neurological sciences Vol. 260; no. 1; pp. 143 - 146 |
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Main Authors: | , , , , , |
Format: | Journal Article |
Language: | English |
Published: |
Shannon
Elsevier B.V
15-09-2007
Elsevier Science |
Subjects: | |
Online Access: | Get full text |
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Summary: | Abstract Preliminary data suggest potential benefit of 5-HT receptor agonists in the treatment of ataxias. We studied the effects of buspirone in a cohort of twenty patients with spinocerebellar ataxia (SCA). Twenty patients were treated in this double-blind, placebo controlled, cross-over trial with either buspirone HCl 30 mg twice daily or placebo for 3 months. Buspirone was not shown to be superior to placebo in the treatment of patients with SCA. |
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ISSN: | 0022-510X 1878-5883 |
DOI: | 10.1016/j.jns.2007.04.019 |