Multiple pulmonary nodules in association with pyoderma gangrenosum

• Published in: Respiratory medicine Vol. 91; no. 8; pp. 493 - 495
• Main Authors: Kasuga, I., Yanagisawa, N., Takeo, C., Koga, M., Kiyokawa, H., Yonemaru, M., Ichinose, Y., Toyama, K.
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 01-09-1997; Elsevier
• Subjects: Anti-Inflammatory Agents - therapeutic use; Biological and medical sciences; Dermatology; Humans; Lung Diseases - complications; Lung Diseases - diagnostic imaging; Lung Diseases - drug therapy; Male; Medical sciences; Middle Aged; Prednisolone - therapeutic use; Pyoderma Gangrenosum - complications; Pyoderma Gangrenosum - drug therapy; Pyoderma Gangrenosum - pathology; Radiography; Skin involvement in other diseases. Miscellaneous. General aspects; Case study; Human; Lung disease; Skin disease; Multiple; Respiratory disease; Lung; Tumor; Nodule; Pyoderma gangrenosum
• ISSN: 0954-6111; 1532-3064
• DOI: 10.1016/S0954-6111(97)90115-3

This report describes a patient with extensive pyoderma gangrenosum in whom there were co-existent lung abnormalities. The patient's X-ray showed peripherally sited multiple pulmonary lesions bilaterally. A lung biopsy showed chronic non-specific inflammatory changes with neutrophil and lymphocyte infiltration which were similar to the skin lesions. This case was diagnosed as multiple aseptic nodules in pyoderma gangrenosum. The pulmonary infiltrative shadows were controlled only with prednisolone treatment. Steroid therapy is considered to be the first choice to control pulmonary lesions of this discase.