Potassium selenocyanate as an efficient selenium source in C–Se cross-coupling catalyzed by copper iodide in water

• Published in: Tetrahedron letters Vol. 52; no. 31; pp. 3978 - 3981
• Main Authors: Kumar, A. Vijay, Reddy, V. Prakash, Reddy, C. Suresh, Rao, K. Rama
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 03-08-2011; Elsevier
• Subjects: Aromatic compounds; Aryl halides; Chemistry; Copper; Copper iodide; Cross coupling; Diaryl selenides; Exact sciences and technology; Halides; Iodides; Noncondensed benzenic compounds; Organic chemistry; Potassium; Potassium selenocyanate; Preparations and properties; Selenides; Tetrahedrons; Water; Water; Potassium selenocyanate; Cross-coupling; Diaryl selenides; Copper iodide; Aryl halides; Organic selenide; Catalytic reaction; Haloarene; Potassium Selenocyanates; Organic halogen compounds; Cross reaction; Benzenic compound; Aromatic compound; Copper I Iodides; Selenium; Heterocyclic compound; Halogen Organic compounds; Successive reaction
• ISSN: 0040-4039; 1873-3581
• DOI: 10.1016/j.tetlet.2011.05.068

An efficient and conceptually new protocol for C–Se cross coupling of potassium selenocyanate with aryl halides via copper-catalyzed cascade reaction has been developed in water. Utilizing this protocol, a variety of aryl and heteroaryl halides were reacted with potassium selenocyanate to afford the corresponding diaryl selenides in moderate to good yields.