Atypical femoral neck stress fracture in a human immunodeficiency virus-infected patient despite anti-osteoporotic treatment: A case report

• Published in: Turkish journal of physical medicine and rehabilitation Vol. 66; no. 3; pp. 364 - 367
• Main Authors: Terlemez, Rana, Sonmez, Mehmet Mesut, Hamidi, Aziz Ahmad, Yilmaz, Figen
• Format: Journal Article
• Language: English; Turkish
• Published: Galenos Yayinevi Tic. Ltd 01-09-2020; Bayçınar Medical Publishing
• Subjects: AIDS treatment; Alendronate; Anti-HIV agents; Antiretroviral agents; Care and treatment; Case Report; Denosumab; Development and progression; Dolutegravir; Fractures (Injuries); Health aspects; Highly active antiretroviral therapy; HIV; HIV patients; Ibandronate sodium; Infection; Osteoporosis
• ISSN: 2587-0823; 1302-0234; 2587-0823
• DOI: 10.5606/tftrd.2020.4286

Both human immunodeficiency virus (HIV) infection and antiretroviral therapy are related to an increased risk of fracture. As a result of the developments in HIV treatment in recent years, life expectancy in HIV-infected patients has increased. Therefore, HIV-related musculoskeletal problems such as osteoporosis and avascular necrosis are more common currently. There are complex mechanisms in HIV-related osteoporosis. The loss of bone mineral density is particularly distinctive in the first months of the therapy. In this report, we present a 54-year-old woman admitted to our clinic with right thigh pain for three months and diagnosed with a femoral neck stress fracture. Keywords: Femur fracture, human immunodeficiency virus, osteoporosis, tenofovir.