Recent developments, characteristics and potential applications of screen-printed electrodes in pharmaceutical and biological analysis

• Published in: Talanta (Oxford) Vol. 146; pp. 801 - 814
• Main Authors: Couto, R.A.S., Lima, J.L.F.C., Quinaz, M.B.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01-01-2016
• Subjects: Biosensing Techniques - methods; Electrochemical detection; Electrochemistry; Electrochemistry - instrumentation; Electrodes; Humans; Miniaturization; Pharmaceutical analysis; Pharmaceutical Preparations - analysis; Printing; Screen-printed electrodes (SPEs); Sensor; Electrochemistry; Electrochemical detection; Screen-printed electrodes (SPEs); Miniaturization; Pharmaceutical analysis; Sensor
• ISSN: 0039-9140; 1873-3573
• DOI: 10.1016/j.talanta.2015.06.011

Screen-printed electrodes (SPEs) have gone through significant improvements over the past few decades with respect to both their format and their printing materials. Thus, SPEs have been successfully applied for the in situ detection of a plethora of analytes in a wide range of sample matrixes due to their advantageous material properties, such as disposability, simplicity, and rapid responses. In particular, the development of electrochemical sensors based on SPEs for pharmaceutical analysis has received massive consideration since they enable the rapid screening of the pharmaceutical compounds in complex matrixes, requiring small volumes of samples and no pre-treatment steps. This review summarizes the design and the working principles of electrochemical sensors based on SPEs applied to the quantification of pharmaceutical and biological compounds.
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•Recent advances in the design and production of screen-printed electrodes (SPEs).•Description of the novel design, methods and materials of SPEs-based sensors.•Review of recent applications of SPEs to pharmaceutical analysis.