Role of scintigraphy in inflammatory bowel disease

The diagnosis of inflammatory bowel disease （IBD） depends on direct endoscopic visualization of the colonic and ileal mucosa and the histological study of the obtained samples. Radiological and scintigraphic methods are mainly used as an adjunct to endoscopy. In this review, we focus on the diagnost...

Full description

Saved in:

Bibliographic Details
Published in:	World journal of gastroenterology : WJG Vol. 15; no. 22; pp. 2693 - 2700
Main Authors:	Stathaki, Maria I, Koukouraki, Sophia I, Karkavitsas, Nikolaos S, Koutroubakis, Ioannis E
Format:	Journal Article
Language:	English
Published:	United States Department of Nuclear Medicine,University Hospital of Heraklion,71110 Heraklion,Crete,Greece%Department of Gastroenterology,University Hospital of Heraklion,71110 Heraklion,Crete,Greece 14-06-2009 The WJG Press and Baishideng
Subjects:	Endoscopy Humans Indium Radioisotopes Inflammatory Bowel Diseases - diagnosis Inflammatory Bowel Diseases - pathology Organotechnetium Compounds Positron-Emission Tomography Radionuclide Imaging - methods Radiopharmaceuticals 内窥镜放射性核素正电子发射断层扫描肠黏膜计算机断层扫描鸡传染性法氏囊病 Technetium-99m pentavalent dimercaptosuccinic acid Intestinal inflammation Crohn's disease Scintigraphy Ulcerative colitis
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	The diagnosis of inflammatory bowel disease （IBD） depends on direct endoscopic visualization of the colonic and ileal mucosa and the histological study of the obtained samples. Radiological and scintigraphic methods are mainly used as an adjunct to endoscopy. In this review, we focus on the diagnostic potential of nuclear medicine procedures. The value of all radiotracers is described with special reference to those with greater experience and more satisfactory results. Tc-99m hexamethylpropylene amine oxime white blood cells remain a widely acceptable scintigraphic method for the diagnosis of IBD, as well as for the evaluation of disease extension and severity. Recently, pentavalent Tc-99m dimercaptosuccinic acid has been recommended as an accurate variant and a complementary technique to endoscopy for the follow-up and assessment of disease activity. Positron emission tomography alone or with computed tomography using fluorine-18 fluorodeoxyglucose appears to be a promising method of measuring inflammation in IBD patients.
Bibliography:	14-1219/R Crohn＇s disease; Technetium-99m pentavalent dimercaptosuccinic acid; Intestinal inflammation; Scintigraphy; Ulcerative colitis Technetium-99m pentavalent dimercaptosuccinic acid Intestinal inflammation S852.218 Scintigraphy Q51 Crohn＇s disease Ulcerative colitis SourceType-Scholarly Journals-1 ObjectType-Commentary-2 content type line 23 ObjectType-Review-1 ObjectType-Editorial-3 Correspondence to: Ioannis E Koutroubakis, MD, PhD, Department of Gastroenterology, Medicine University Hospital of Heraklion, PO Box 1352, 71110 Heraklion, Crete, Greece. ktjohn@her.forthnet.gr Fax: +30-2810-542085 Telephone: +30-2810-392253 Author contributions: Stathaki MI, Koukouraki SI reviewed the literature, wrote the first draft of the paper; Karkavitsas NS and Koutroubakis IE provided the idea, performed the review, and edited the manuscript.
ISSN:	1007-9327 2219-2840
DOI:	10.3748/wjg.15.2693