Alterations in T cells of cancer-bearers: whence specificity?

T cells of tumor-bearing mice and cancer patients have been reported to have altered signal-transduction machinery. These alterations have been implicated in immunological suppression. Here, Daniel Levey and Pramod Srivastava critically examine the evidence for these alterations in the context of th...

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Bibliographic Details
Published in:	Immunology today (Amsterdam. Regular ed.) Vol. 17; no. 8; pp. 365 - 368
Main Authors:	Levey, Daniel L., Srivastava, Pramod K.
Format:	Journal Article
Language:	English
Published:	England Elsevier B.V 01-08-1996
Subjects:	Animals Epitopes - immunology Humans Neoplasms - immunology Neoplasms, Experimental - immunology Signal Transduction - immunology T-Lymphocytes - immunology T-Lymphocytes - metabolism
Online Access:	Get full text
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Summary:	T cells of tumor-bearing mice and cancer patients have been reported to have altered signal-transduction machinery. These alterations have been implicated in immunological suppression. Here, Daniel Levey and Pramod Srivastava critically examine the evidence for these alterations in the context of the tumor specificity of immunological unresponsiveness in tumor-bearing hosts.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 ObjectType-Review-3 content type line 23 ObjectType-Feature-3 ObjectType-Review-1
ISSN:	0167-5699
DOI:	10.1016/0167-5699(96)10013-X