A review on structure, extraction, and biological activities of polysaccharides isolated from Cyclocarya paliurus (Batalin) Iljinskaja

• Published in: International journal of biological macromolecules Vol. 156; pp. 420 - 429
• Main Authors: Kakar, Mohib Ullah, Naveed, Muhammad, Saeed, Muhammad, Zhao, Shicong, Rasheed, Madiha, Firdoos, Sundas, Manzoor, Robina, Deng, Yulin, Dai, Rongji
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01-08-2020
• Subjects: Anti-cancer activity; Antineoplastic Agents - chemistry; Antineoplastic Agents - isolation & purification; Antineoplastic Agents - pharmacology; Antioxidant activity; Antioxidants - chemistry; Antioxidants - isolation & purification; Antioxidants - pharmacology; Chemical Fractionation; Cyclocarya paliurus; Immunologic Factors - chemistry; Immunologic Factors - isolation & purification; Immunologic Factors - pharmacology; Juglandaceae - chemistry; Microwaves; Molecular Structure; Plant Extracts - chemistry; Plant Extracts - isolation & purification; Plant Extracts - pharmacology; Polysaccharides; Polysaccharides - chemistry; Polysaccharides - isolation & purification; Polysaccharides - pharmacology; Polysaccharides modification; Structure-Activity Relationship; Ultrasonic Waves; Polysaccharides; Polysaccharides modification; Antioxidant activity; Cyclocarya paliurus; Anti-cancer activity
• ISSN: 0141-8130; 1879-0003
• DOI: 10.1016/j.ijbiomac.2020.04.022

Cyclocarya paliurus is essential and only living specie of the genus Cyclocarya Iljinskaja. The leaves of this plant have been extensively used as food in the form of tea and green vegetable. Many compounds have been isolated from this plant, and their useful aspects explored, including the polysaccharides. Studies conducted on leaves show that different methods of extraction have been used, as well as a combination of different techniques that have been applied to isolate polysaccharides from the leaves. Their structure has been elucidated because the activity of polysaccharides mainly depends upon their composition. It has been reported that different activities exhibited by the isolated crude, purified as well as modified polysaccharides include, anticancer, anti-inflammatory, antioxidant, antimicrobial, anti-hyperlipidemic and anti-diabetic activities. In some studies, a comparison of crude extract, as well as purified polysaccharide, has been performed. In this review, we have summarized all the available literature available on the methods of extraction, structure, and biological activities of polysaccharides from the leaves of C. paliurus and indicated the potential research areas that should be focused on future studies. We believe that this review will provide an up to date knowledge regarding polysaccharides of C. paliurus for the researchers.