Abrupt Increase in Rate of Imipenem Resistance in Acinetobacter baumannii Complex Strains Isolated from General Hospitals in Korea and Correlation With Carbapenem Administration During 2002-2013

• Published in: Annals of laboratory medicine Vol. 38; no. 2; pp. 179 - 181
• Main Authors: Kim, Young Ah, Park, Yoon Soo, Youk, Taemi, Lee, Hyukmin, Lee, Kyungwon
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Society for Laboratory Medicine 01-03-2018; 대한진단검사의학회
• Subjects: Acinetobacter baumannii - drug effects; Acinetobacter baumannii - genetics; Acinetobacter baumannii - isolation & purification; Acinetobacter Infections - drug therapy; Anti-Bacterial Agents - pharmacology; Anti-Bacterial Agents - therapeutic use; beta-Lactamases - genetics; Databases, Factual; Drug Resistance, Bacterial; Hospitals, General; Humans; Imipenem - pharmacology; Imipenem - therapeutic use; Letter to the Editor; Republic of Korea; 병리학; Republic of Korea
• ISSN: 2234-3806; 2234-3814
• DOI: 10.3343/alm.2018.38.2.179

Dear Editor, Acinetobacter baumannii is a cause of healthcare-associated infections and one of the most important pathogens found in intensive care units (ICUs). The recent dramatic spread of carbapenem-resistant A. baumannii complex (CRAB) in Korea has raised substantial concern in medical practice owing to the lack of adequate therapeutic options [1, 2]. It is well-known that the selective pressure of antibiotics contributes to emergence of new resistant strains [3]. However, there is no sufficient evidence for the association between carbapenem administration and emergence of imipenem-resistant A KCI Citation Count: 5