Expression of translationally controlled tumor protein in heat-stressed human dental pulp cells

Highlights • We examine the effects of heat stress on human dental pulp cells. • Heat stress induces caspase 3 activation and up-regulates TCTP mRNA expression. • The effect of TCTP on heat-stressed cells depends on each individual and TCTP concentration. • TCTP did not play a key role on pulp cell...

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Published in:	Archives of oral biology Vol. 60; no. 10; pp. 1474 - 1481
Main Authors:	Jirachotikoon, Canussanun, Tannukit, Sissada, Kedjarune-Leggat, Ureporn
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01-10-2015
Subjects:	Adolescent Adult Advanced Basic Science Animals Apoptosis Biomarkers, Tumor - biosynthesis Biomarkers, Tumor - genetics Caspase 3 - metabolism Cell Death Cell Survival - physiology Cells, Cultured Dental pulp Dental Pulp - cytology Dental Pulp - metabolism Dental Pulp - physiology Dentistry Down-Regulation Enzyme Activation Gene Expression Regulation Heat stress Hot Temperature Humans Penaeidae Real-Time Polymerase Chain Reaction Recombinant Proteins - biosynthesis Recombinant Proteins - genetics RNA, Messenger - genetics RNA, Messenger - metabolism TCTP Up-Regulation Young Adult Heat stress TCTP Apoptosis Dental pulp
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Summary:	Highlights • We examine the effects of heat stress on human dental pulp cells. • Heat stress induces caspase 3 activation and up-regulates TCTP mRNA expression. • The effect of TCTP on heat-stressed cells depends on each individual and TCTP concentration. • TCTP did not play a key role on pulp cell recovery from heat stress.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0003-9969 1879-1506
DOI:	10.1016/j.archoralbio.2015.07.011