Lupus Masquerading as a Drug Reaction in HIV Infection

Lupus Masquerading as a Drug Reaction in HIV Infection

An HIV-positive female on antiretroviral therapy (ART) presented with an annular eruption diagnosed as a drug reaction based on histology of a lichenoid dermatitis. She responded to oral steroid therapy and discontinuation, but progressed to develop features in keeping with cutaneous lupus. Although...

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Bibliographic Details
Published in:Dermatopathology (Basel, Switzerland) Vol. 6; no. 2; pp. 85 - 90
Main Authors: Mosam, Anisa, Hoosen, Koraisha, Dlova, Ncoza C.
Format: Journal Article
Language:English
Published: Basel, Switzerland S. Karger AG 26-06-2019
MDPI AG
Subjects:
Antiretroviral therapy
Case Report
HIV infection
Subacute lupus
HIV infection
Antiretroviral therapy
Subacute lupus
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Description
Summary:An HIV-positive female on antiretroviral therapy (ART) presented with an annular eruption diagnosed as a drug reaction based on histology of a lichenoid dermatitis. She responded to oral steroid therapy and discontinuation, but progressed to develop features in keeping with cutaneous lupus. Although the antinuclear factor remained negative, her low serum complement levels, histology, and clinical features pointed to a diagnosis of subacute lupus in the setting of HIV infection. She responded well to antimalarial therapy and recommenced ART.
ISSN:2296-3529
2296-3529
DOI:10.1159/000496336