CD142 plays an important role in the mobility of colorectal cancer cells

CD142 promotes cell mobility, which contributes to carcinogenesis. However, the role of CD142 on colorectal cancer (CRC) mobility is unclear. This study showed that CD142 expression increased in CRC tissues, especially in those with invasion or metastasis. The positive sorting or overexpression of C...

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Bibliographic Details
Published in:	Bioscience, biotechnology, and biochemistry Vol. 84; no. 9; pp. 1856 - 1860
Main Authors:	Gao, Qin, Chen, Zhongbiao, He, Yang, Hou, Zhibin, Ye, Ruifeng, Xue, Wanlin, Lin, Jiahui, Tu, Xiaohuang
Format:	Journal Article
Language:	English
Published:	England Taylor & Francis 01-09-2020
Subjects:	CD142 Cell Line, Tumor Cell Movement Colorectal Neoplasms - pathology CRC Gene Expression Regulation, Neoplastic Humans invasion metastasis mobility Neoplasm Invasiveness Neoplasm Metastasis Thromboplastin - metabolism CD142 mobility invasion CRC metastasis
Online Access:	Get full text
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Summary:	CD142 promotes cell mobility, which contributes to carcinogenesis. However, the role of CD142 on colorectal cancer (CRC) mobility is unclear. This study showed that CD142 expression increased in CRC tissues, especially in those with invasion or metastasis. The positive sorting or overexpression of CD142 promoted the invasion and migration of CRC cells. Overall, CD142 may be responsible for CRC mobility.
ISSN:	0916-8451 1347-6947
DOI:	10.1080/09168451.2020.1772039