Dopamine determines how reward overrides risk

Why do animals pursue reward in the face of punishment? Dopamine-releasing neurons that promote reward-seeking behaviour indirectly impair those that encode punishment avoidance, affecting decisions on risk. Opposing neural pathways influence reward-seeking in fruit flies.

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Bibliographic Details
Published in:	Nature (London) Vol. 623; no. 7986; pp. 258 - 259
Main Authors:	Scaplen, Kristin M., Kaun, Karla R.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 09-11-2023 Nature Publishing Group
Subjects:	631/378 631/601/18 692/698/1688/64 Addictions Addictive behaviors Alcohol Behavior Brain Dopamine Gene expression Humanities and Social Sciences Hunger multidisciplinary Mushroom bodies Neurons Neurosciences News And Views Reinforcement Reward Science Thirst Rhode Island United States > US Brain Neuroscience Animal behaviour
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Description
Summary:	Why do animals pursue reward in the face of punishment? Dopamine-releasing neurons that promote reward-seeking behaviour indirectly impair those that encode punishment avoidance, affecting decisions on risk. Opposing neural pathways influence reward-seeking in fruit flies.
Bibliography:	content type line 23 SourceType-Scholarly Journals-1 ObjectType-News-1
ISSN:	0028-0836 1476-4687 1476-4687
DOI:	10.1038/d41586-023-03085-4