The birth of artemisinin

As the first-line antimalarial drugs, artemisinins gained wide acceptance after the emergence of resistance to chloroquine in the 1950s. Artemisinin-based drugs have saved lives, especially in developing countries. The discovery of artemisinin was unique, timely, and fascinating, and the benefits of...

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Bibliographic Details
Published in:	Pharmacology & therapeutics (Oxford) Vol. 216; p. 107658
Main Authors:	Ma, Nan, Zhang, Ziyue, Liao, Fulong, Jiang, Tingliang, Tu, Youyou
Format:	Journal Article
Language:	English
Published:	England Elsevier Inc 01-12-2020
Subjects:	Antimalarial Artemisinin Qinghaosu Antimalarial Qinghaosu MOA Artemisinin WHO ACTs
Online Access:	Get full text
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Summary:	As the first-line antimalarial drugs, artemisinins gained wide acceptance after the emergence of resistance to chloroquine in the 1950s. Artemisinin-based drugs have saved lives, especially in developing countries. The discovery of artemisinin was unique, timely, and fascinating, and the benefits of artemisinin were with far-reaching implications. Herein, we will give a brief description of various aspects of the development of artemisinin and discuss the position and perspectives of artemisinin-based drugs.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	0163-7258 1879-016X
DOI:	10.1016/j.pharmthera.2020.107658