Rapid Progression of Angioimmunoblastic T Cell Lymphoma Following BNT162b2 mRNA Vaccine Booster Shot: A Case Report

Since nucleoside-modified mRNA vaccines strongly activate T follicular helper cells, it is important to explore the possible impact of approved SARS-CoV-2 mRNA vaccines on neoplasms affecting this cell type. Herein, we report and discuss unexpected rapid progression of lymphomatous lesions after adm...

Full description

Saved in:

Bibliographic Details
Published in:	Frontiers in medicine Vol. 8; p. 798095
Main Authors:	Goldman, Serge, Bron, Dominique, Tousseyn, Thomas, Vierasu, Irina, Dewispelaere, Laurent, Heimann, Pierre, Cogan, Elie, Goldman, Michel
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 25-11-2021
Subjects:	angioimmunoblastic COVID-19 follicular lymphoma Medicine mRNA vaccine T cell COVID-19 angioimmunoblastic T cell follicular lymphoma mRNA vaccine
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Since nucleoside-modified mRNA vaccines strongly activate T follicular helper cells, it is important to explore the possible impact of approved SARS-CoV-2 mRNA vaccines on neoplasms affecting this cell type. Herein, we report and discuss unexpected rapid progression of lymphomatous lesions after administration of a BNT162b2 mRNA vaccine booster in a man recently diagnosed with AITL.
Bibliography:	This article was submitted to Pathology, a section of the journal Frontiers in Medicine Reviewed by: Tzvi Dwolatzky, Technion Israel Institute of Technology, Israel; Laurent Pierre Nicod, University of Lausanne, Switzerland Edited by: Ihsan Ullah, Khyber Medical University, Pakistan
ISSN:	2296-858X 2296-858X
DOI:	10.3389/fmed.2021.798095