Synthesis and Antinociceptive Activity of (5-Chloro-2-benzothiazolinon-3-yl)acetamide Derivatives

The synthesis of (5‐chloro‐2‐benzothiazolinon‐3‐yl)acetamide derivatives is reported. The structure of these compounds is supported by their IR and 1H‐NMR spectra. The compounds were tested for antinociceptive activity.

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Bibliographic Details
Published in:	Archiv der Pharmazie (Weinheim) Vol. 333; no. 10; pp. 337 - 340
Main Authors:	Önkol, T., Dogruer, D. S., Ito, S., Sahin, M. F.
Format:	Journal Article
Language:	English
Published:	Weinheim WILEY-VCH Verlag GmbH 01-10-2000 WILEY‐VCH Verlag GmbH Wiley-VCH
Subjects:	(5-Chloro-2-benzothiazolinon-3-yl)acetamide Analgesics Analgesics - chemical synthesis Animals antinociceptive activity Benzothiazoles Biological and medical sciences Male Medical sciences Mice Neuropharmacology NMR Pharmacology. Drug treatments Piperazines - chemical synthesis Piperazines - pharmacology Structure-Activity Relationship Sulfur nitrogen heterocycle Rodentia Benzothiazole derivatives Vertebrata Mammalia Analgesic Structure activity relation Mouse Animal Chlorine Organic compounds Bicyclic compound Carboxamide Aromatic compound Chemical synthesis
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Description
Summary:	The synthesis of (5‐chloro‐2‐benzothiazolinon‐3‐yl)acetamide derivatives is reported. The structure of these compounds is supported by their IR and 1H‐NMR spectra. The compounds were tested for antinociceptive activity.
Bibliography:	istex:12E8D06F5868033A6F9F77E78CEEC812451E1B19 ark:/67375/WNG-7QC95THM-2 ArticleID:ARDP337 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0365-6233 1521-4184
DOI:	10.1002/1521-4184(200010)333:10<337::AID-ARDP337>3.0.CO;2-A