Effectiveness of a Fourth Dose of COVID-19 mRNA Vaccine Against Omicron Variant Among Elderly People in Singapore

Tan et al discuss a study which aims to estimate the effectiveness of a fourth mRNA vaccine dose against symptomatic SARS-CoV-2 infection, COVID-19-related hospitalization, and severe COVID-19 in persons 80 years of age or older. The study was conducted to inform public health policy under the Infec...

Full description

Saved in:

Bibliographic Details
Published in:	Annals of internal medicine Vol. 175; no. 11; pp. 1622 - 1623
Main Authors:	Tan, Celine Y, Chiew, Calvin J, Lee, Vernon J, Ong, Benjamin, Lye, David Chien, Tan, Kelvin Bryan
Format:	Journal Article
Language:	English
Published:	United States American College of Physicians 01-11-2022
Subjects:	Aged COVID-19 - prevention & control COVID-19 Vaccines Elder care Hospitalization Humans Letters Medical research mRNA Vaccines SARS-CoV-2 - genetics Severe acute respiratory syndrome coronavirus 2 Singapore - epidemiology Singapore
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Tan et al discuss a study which aims to estimate the effectiveness of a fourth mRNA vaccine dose against symptomatic SARS-CoV-2 infection, COVID-19-related hospitalization, and severe COVID-19 in persons 80 years of age or older. The study was conducted to inform public health policy under the Infectious Diseases Act, Singapore, with exemption from ethics review. This study, based on comprehensive health care administrative data, provides evidence that a fourth mRNA vaccine dose confers additional sustained protection against hospitalization and severe disease from COVID-19 in an elderly Asian population during Omicron variant epidemic.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M22-2042.
ISSN:	0003-4819 1539-3704
DOI:	10.7326/M22-2042