Hyperthymic temperament predicts neural responsiveness for nonmonetary reward

• Published in: PCN reports Vol. 2; no. 3; pp. e140 - n/a
• Main Authors: Ogura, Yukiko, Wakatsuki, Yumi, Hashimoto, Naoki, Miyamoto, Tamaki, Nakai, Yukiei, Toyomaki, Atsuhito, Tsuchida, Yukio, Nakagawa, Shin, Inoue, Takeshi, Kusumi, Ichiro
• Format: Journal Article
• Language: English
• Published: Australia John Wiley & Sons, Inc 01-09-2023; John Wiley and Sons Inc; Wiley
• Subjects: Feedback; fMRI; hyperthymic temperament; Magnetic resonance imaging; major depressive disorder; Mental depression; Mental disorders; monetary incentive delay; Monetary incentives; Neurobiology; Noncompliance; Original; Physiology; Questionnaires; somatosensory area; fMRI; monetary incentive delay; major depressive disorder; hyperthymic temperament; somatosensory area
• ISSN: 2769-2558; 2769-2558
• DOI: 10.1002/pcn5.140

Hyperthymic temperament is a cheerful action orientation that is suggested to have a protective effect on depressive symptoms. We recently reported that hyperthymic temperament can positively predict activation of reward-related brain areas in anticipation of monetary rewards, which could serve as a biomarker of hyperthymic temperament. However, the relationship between hyperthymic temperament and neural responsiveness to nonmonetary rewards (i.e., feedback indicating success in a task) remains unclear.
Healthy participants performed a modified monetary incentive delay task inside a functional magnetic resonance imaging scanner. To examine the effect of nonmonetary positive feedback, the participants performed feedback and no-feedback trials. We explored brain regions whose neural responsiveness to nonmonetary rewards was predicted by hyperthymic temperament.
There was premotor area activation in anticipation of a nonmonetary reward, which was negatively predicted by hyperthymic temperament. Moreover, brain areas located mainly in the primary somatosensory area and somatosensory association area were activated by performance feedback, which was positively predicted by hyperthymic temperament.
We found that hyperthymic temperament is related to neural responsiveness to both monetary and nonmonetary rewards. This may be related to the process of affective regulation in the somatosensory area.