Biomonitoring of polycyclic aromatic hydrocarbons in human urine

Biomonitoring of polycyclic aromatic hydrocarbons in human urine

Measurement of polycyclic aromatic hydrocarbons (PAH) metabolites in human urine is the method of choice to determine occupational and/or environmental exposure of an individual to PAH, in particular, when multiple routes of exposure have to be taken into account. Requirements for methods of biomoni...

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Bibliographic Details
Published in:Journal of Chromatography B Vol. 778; no. 1; pp. 31 - 47
Main Authors: Jacob, Jürgen, Seidel, Albrecht
Format: Book Review Journal Article
Language:English
Published: Netherlands Elsevier B.V 05-10-2002
Subjects:
Environmental Monitoring
Humans
Polycyclic Compounds - pharmacokinetics
Polycyclic Compounds - urine
Polynuclear aromatic hydrocarbons
Polynuclear aromatic hydrocarbons
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Abstract Measurement of polycyclic aromatic hydrocarbons (PAH) metabolites in human urine is the method of choice to determine occupational and/or environmental exposure of an individual to PAH, in particular, when multiple routes of exposure have to be taken into account. Requirements for methods of biomonitoring PAH metabolites in urine are presented. Studies using 1-hydroxypyrene or phenanthrene metabolites including its phenols and dihydrodiols are summarized. The role of these PAH metabolites as established biomarkers and also more recent developments of PAH biomonitoring are discussed.
AbstractList Measurement of polycyclic aromatic hydrocarbons (PAH) metabolites in human urine is the method of choice to determine occupational and/or environmental exposure of an individual to PAH, in particular, when multiple routes of exposure have to be taken into account. Requirements for methods of biomonitoring PAH metabolites in urine are presented. Studies using 1-hydroxypyrene or phenanthrene metabolites including its phenols and dihydrodiols are summarized. The role of these PAH metabolites as established biomarkers and also more recent developments of PAH biomonitoring are discussed.
Author Jacob, Jürgen
Seidel, Albrecht
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  surname: Seidel
  fullname: Seidel, Albrecht
BackLink https://www.ncbi.nlm.nih.gov/pubmed/12376115$$D View this record in MEDLINE/PubMed
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Keywords Polynuclear aromatic hydrocarbons
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PMID 12376115
PageCount 17
ParticipantIDs crossref_primary_10_1016_S0378_4347_01_00467_4
pubmed_primary_12376115
elsevier_sciencedirect_doi_10_1016_S0378_4347_01_00467_4
PublicationCentury 2000
PublicationDate 2002-10-05
PublicationDateYYYYMMDD 2002-10-05
PublicationDate_xml – month: 10
  year: 2002
  text: 2002-10-05
  day: 05
PublicationDecade 2000
PublicationPlace Netherlands
PublicationPlace_xml – name: Netherlands
PublicationTitle Journal of Chromatography B
PublicationTitleAlternate J Chromatogr B Analyt Technol Biomed Life Sci
PublicationYear 2002
Publisher Elsevier B.V
Publisher_xml – name: Elsevier B.V
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Snippet Measurement of polycyclic aromatic hydrocarbons (PAH) metabolites in human urine is the method of choice to determine occupational and/or environmental...
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SubjectTerms Environmental Monitoring
Humans
Polycyclic Compounds - pharmacokinetics
Polycyclic Compounds - urine
Polynuclear aromatic hydrocarbons
Title Biomonitoring of polycyclic aromatic hydrocarbons in human urine
URI https://dx.doi.org/10.1016/S0378-4347(01)00467-4
https://www.ncbi.nlm.nih.gov/pubmed/12376115
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