A Survey of the Neuro-Oncology Landscape

• Published in: Journal of clinical neurology (Seoul, Korea) Vol. 14; no. 1; pp. 8 - 15
• Main Authors: Lukas, Rimas V, Wu, Jing, Dey, Mahua, Buerki, Robin A, Byrne, Richard W, Dohrmann, George J
• Format: Journal Article
• Language: English
• Published: Korea (South) Korean Neurological Association 01-01-2018; 대한신경과학회
• Subjects: Review; 신경과학; laser ablation; tumor treating fields; viral therapy; isocitrate dehydrogenase; brain metastases; neuro-oncology; gene therapy; glioma; neurosurgery
• ISSN: 1738-6586; 2005-5013
• DOI: 10.3988/jcn.2018.14.1.8

The field of neuro-oncology is evolving rapidly. Many important advances have recently been reported, and other promising investigations have the potential to soon make substantial impacts in the field, especially in the areas of high-grade gliomas and brain metastases. We present an overview of the current status of this field, highlighting the key recent advances as well as representative work of key clinical investigations, since these concepts have the potential to influence clinical management if they are demonstrated to be safe and efficacious. This overview includes some work that has only appeared in abstract form in order to provide a timely understanding of how the field is actively changing and what may lie on the horizon. We focus on both medical and surgical neuro-oncology advances in this highly multidisciplinary subspecialty.