Plant-Derived Vesicle-Like Nanoparticles: Clinical Application Exploration and Challenges

The utilization of plant-derived vesicle-like nanoparticles (PDVLNs) has shown effectiveness in the prevention/treatment of inflammatory-mediated diseases, malignancies, and immune-related diseases, such as acute liver injury, allergic asthma, gastric cancer and so on. This highlights the promising...

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Bibliographic Details
Published in:	International journal of nanomedicine Vol. 18; pp. 5671 - 5683
Main Authors:	He, Wenfang, Zheng, Siqiang, Zhang, Hua, Gao, Bowen, Jin, Juan, Zhang, Mingzhen, He, Qiang
Format:	Journal Article
Language:	English
Published:	Dove 01-01-2023 Dove Medical Press
Subjects:	anti-inflammatory antitumor extraction methods immune regulation plant-derived vesicle-like nanoparticles Review
Online Access:	Get full text
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Summary:	The utilization of plant-derived vesicle-like nanoparticles (PDVLNs) has shown effectiveness in the prevention/treatment of inflammatory-mediated diseases, malignancies, and immune-related diseases, such as acute liver injury, allergic asthma, gastric cancer and so on. This highlights the promising potential of PDVLNs as biotherapeutics. Furthermore, it should be noted that PDVLNs possess the ability to function as both natural and engineered drug carriers, making them an appealing option. This review aims to present the appropriate extraction methods of PDVLNs, summarize the applications of PDVLNs in different diseases, and provide an outlook on the prospects of PDVLNs. At the same time, the authors also express their discussion on the current limitations of PDVLNs.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 These authors contributed equally to this work
ISSN:	1178-2013 1176-9114 1178-2013
DOI:	10.2147/IJN.S428647