Autoimmune pancreatitis with atypical imaging findings that mimicked an endocrine tumor
Autoimmune pancreatitis (AIP) is a rare cause of recurrent acute pancreatitis or chronic pancreatitis in middle-aged patients, and is characterised by a marked infiltration of lymphocytes and plasma cells in pancreatic tissue. Diagnosis of focal forms can be difficult as AIP may mimic pancreatic ade...
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| Summary: | Autoimmune pancreatitis (AIP) is a rare cause of recurrent acute pancreatitis or chronic pancreatitis in middle-aged patients, and is characterised by a marked infiltration of lymphocytes and plasma cells in pancreatic tissue. Diagnosis of focal forms can be difficult as AIP may mimic pancreatic adenocarcinoma. Pediatric cases of AIP are exceptional. We report the case of a 15-year-old girl who had a focal AIP and associated cholangitis, with a very unusual vascularized mass that mimicked a pancreatic endocrine tumor. The diagnosis was obtained by a pancreatic biopsy, thus avoiding surgical resection, and all the clinical, biological and radiological abnormalities resolved after steroid therapy with 6 mo of follow-up. |
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| Bibliography: | ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3 Author contributions: Neuzillet C collected and analyzed data; El Hajjam M performed radiological examinations; Palazzo L performed endoscopic explorations; Fabre M performed pathological examinations; Lepère C, El Hajjam M, Fabre M, Turki H, Hammel P and Rougier P contributed reagents; Neuzillet C and Mitry E wrote the paper. Correspondence to: Emmanuel Mitry, Professor, Department of Gastroenterology and Digestive Oncology, Ambroise Paré Hospital, 9, avenue Charles de Gaulle, 92100 Boulogne-Billancourt, France. emmanuel.mitry@apr.aphp.fr Telephone: +33-1-49095874 Fax: +33-1-49094508 |
| ISSN: | 1007-9327 2219-2840 |
| DOI: | 10.3748/wjg.v16.i23.2954 |