Familial Carney complex with biatrial cardiac myxoma

• Published in: Journal of cardiology cases Vol. 15; no. 5; pp. 155 - 157
• Main Authors: Takigami, Masao, MD, Kawata, Masahito, MD PhD, Kintsu, Masayuki, MD, Kodaira, Mutsuki, MD, Sogabe, Koji, MD, Kato, Yukinori, MD, Matsuura, Takeshi, MD, Kamemura, Kohei, MD PhD, Hirayama, Yasutaka, MD, Adachi, Kazumasa, MD PhD, Matsuura, Akira, MD PhD, Sakamoto, Susumu, MD PhD, Tobe, Satoshi, MD PhD, Hamamoto, Kae, MD, Kadoya, Manabu, MD, Koyama, Hidenori, MD PhD
• Format: Journal Article
• Language: English
• Published: Japan Elsevier Ltd 01-05-2017; Japanese College of Cardiology
• Subjects: Cardiovascular; Carney complex; Echocardiography; Endocrine abnormalities; Familial; Myxoma; Endocrine abnormalities; Myxoma; Echocardiography; Familial; Carney complex
• ISSN: 1878-5409; 1878-5409
• DOI: 10.1016/j.jccase.2016.12.007

Abstract We report a case of Carney complex (CNC) with biatrial cardiac myxoma. The patient had left and right atrial myxomas which were resected in a surgery. She showed bilateral adrenal tumors and multiple mammary tumors. She had pigmentation on her lower lip. Previously, her daughter was also diagnosed with CNC with cardiac myxoma. Both of them showed mutations in the PRKAR1A gene. < Learning objective: Carney complex is a syndrome with skin pigmentation, myxomas, and endocrine abnormalities. It is an autosomal dominant disease and shows PRKAR1A gene mutation. We experienced a rare case of familial Carney complex with biatrial cardiac myoxomas found by echocardiography and treated surgically.>