Volumetric assessment of Posterior cranial fossa in a West African population

• Published in: World neurosurgery: X Vol. 22; p. 100334
• Main Authors: Ogolo, Donald E., Ajare, E.C., Ndubuisi, C.A., Okwuoma, Okwunodulu, Nnama, Sunday, Ohaegbulam, S.C.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01-04-2024; Elsevier
• Subjects: Chiari 1 malformation; infratentorial fossa; Original; posterior cranial fossa; syringomyelia; volumetric analysis; West Africa; Chiari 1 malformation; infratentorial fossa; syringomyelia; posterior cranial fossa; volumetric analysis; West Africa
• ISSN: 2590-1397; 2590-1397
• DOI: 10.1016/j.wnsx.2024.100334

Background and Objectives: Posterior fossa pathologies can have potentially devastating outcomes. The volumetric capacity of this fossa, known to have ethnoregional variations, can thus be critical in determining outcomes and intervention measures and approaches to pathologies involving this region. This study aimed to evaluate the normal posterior fossa volumes within the West-African subpopulation. Methods: This was a descriptive study of all patients presenting for a cranial imaging study at the study location within a two-year period using a 1.5T MRI of this cranial region. Obtained data included the transverse and anteroposterior diameters, and the height of this fossa and the obtained data was analyzed. P values < 0.05 was statistically significant. Results: A total of 315 patients were recruited (165 males and 150 females). The average posterior fossa transverse diameter, anteroposterior diameter and height were 108.19 mm, 71.58 mm and 35.53 mm respectively for males, and 105.7 mm, 66.48 mm, and 34.24 mm for females respectively. The average posterior fossa volume for males (292.36 cm3) was significantly higher than for females (252.90 cm3) (p= 0.0038). The highest average posterior fossa volume was between 16-30 years for males and above 75 years for females. Conclusion: Posterior cranial fossa volumes for the West African population is significantly higher than those obtained for other regions. In addition to being beneficial in some posterior fossa space occupying lesions, this larger volume can explain the relative rarity and sexual preferences of some posterior fossa congenital abnormalities like Chiari-1 malformation amongst the West African population